Epithalon

Epithalon · 50mg

Research peptide

Synthetic tetrapeptide · telomerase and melatonin · short longevity cycles

Moderate evidence
Compounding pharmacies in United States can now prepare it · Oct 2026What this means ›
🇺🇸 United States · Compounding pharmacies may prepare it

Since October 2026, the FDA allows compounding pharmacies in United States to prepare it with a prescription: the step that followed its advisory committee's favourable vote. Next step: the FDA adding it permanently to its list of substances for compounding.

Our vial is research material (RUO), not a pharmacy preparation.

Source: FDA · oct 2026

Overview

What has it been researched for?

  • Activates telomerase and protects chromosomes Main focusEarly evidence
  • Cellular longevity: sirtuins and repairEarly evidence
  • Protects the retina and the eyeModerate evidence
  • Deeper sleepEarly evidence

Research protocols

The SBL research protocol and what the literature reports. Not medical advice.

SBL research protocol · no established clinical regimen in people

Dose
5 mg
Frequency
diario · noche
Duration
2 weeks
Route
Subcutaneous
Evidence level
Human pilot

Tools

Evidence and studies

See studies →

Protocols

Research protocols

SBL research protocol · no established clinical regimen in people

Research use, with no established clinical regimen in people.

Dose
5 mg
Frequency
diario · noche
Timing
noche
Duration
2 weeks
Break
20 weeks
Route
Subcutaneous
Evidence level
Human pilot

Example dose

05010030
30 u= 5 mg

100-unit U-100 insulin syringe · Starting dose of its protocol, with 3 ml of water in the 50 mg vial.

What it pairs with

No pairings are recorded for this vial yet.

Preparation and dosing

Quick reference

Vial50 mg
Diluent3 ml
Concentration16.67 mg/ml
1 unit =0.167 mg

Preparation

Diluent
Bacteriostatic water

Open calculator →See the guide →

Evidence

Each effect with its evidence level and, where available, its source.

Strong evidence(0)Moderate evidence(1)Early evidence(3)
  • Activates telomerase and protects chromosomesPreclinicalSee study · 2025
  • Cellular longevity: sirtuins and repairExtrapolatedSee study · 2006
  • Protects the retina and the eyeHuman pilotSee study · 2002
  • Deeper sleepExtrapolatedSee study · 2007

The science

Mechanisms, studies and references

Pineal tetrapeptide

Safety

It makes sense if you want

  • Longevity & deep anti-aging
  • Deep sleep & better rest
  • Calm, mood & less anxiety

It does not make sense if

  • Active cancer or oncology treatment in the last 5 years
  • Pregnancy or breastfeeding

The certificate of analysis (CoA) certifies the identity and purity of the batch. It does not certify safety of use.

Verify your batch →

For research use only (RUO). This consult is educational and does not replace your doctor.

Questions

Frequently asked questions

What is it reconstituted with, and how much?

With bacteriostatic water: 3 ml into the 50 mg vial, giving 16.67 mg/ml.

What is the starting dose of the research protocol?

5 mg, diario · noche. This is the SBL research protocol, with no established clinical regimen in people.

How long is the cycle, and how long does a vial last?

2 weeks ON / ~5 months rest. At the starting dose, the 50 mg vial lasts ~1.4 sem.

Which route is used in research?

Subcutaneous.

When does it make no sense?

It makes no sense with: Active cancer or oncology treatment in the last 5 years, Pregnancy or breastfeeding. Details in the Safety tab.

How do I check my batch?

With the code on the vial, in the verifier. The CoA certifies the identity and purity of the batch, not safety of use.

Verify your batch →

See kit

For research use only (RUO). This consult is educational and does not replace your doctor.