GHK-Cu

GHK-Cu

Research peptide

Copper tripeptide · collagen and firmness with human evidence · anti-inflammatory and repair beyond the skin

Early evidence
Research stage · cosmetic ingredient in United States and European UnionWhat this means ›
🇪🇺 European Union · Cosmetic ingredient🇺🇸 United States · Cosmetic ingredient

It is not an approved drug: it is a recognised cosmetic ingredient in United States and European Union. GHK-Cu is not an approved drug. It is a copper peptide with decades of dermatological literature and established cosmetic use.

Overview

What has it been researched for?

  • Closes wounds and ulcers Main focusEarly evidence
  • Firmer, denser skin: more collagenEarly evidence
  • Antioxidant: less oxidative stressEarly evidence
  • Lowers inflammationEarly evidence
  • Nerve regenerationEarly evidence
  • Protects the lungEarly evidence
  • Denser hair, less sheddingEarly evidence
  • Cellular longevity: sirtuins and repairEarly evidence

Research protocols

The SBL research protocol and what the literature reports. Not medical advice.

SBL research protocol · no established clinical regimen in people

Dose
1 → 2 mg
Frequency
diario
Duration
12 weeks
Route
Subcutaneous
Evidence level
Extrapolated

Tools

Evidence and studies

See studies →

Protocols

Research protocols

SBL research protocol · no established clinical regimen in people

Research use, with no established clinical regimen in people.

Dose
1 → 2 mg
Frequency
diario
Timing
noche
Duration
12 weeks
Break
4 weeks
Route
Subcutaneous
Evidence level
Extrapolated

Example dose

015306
6 u= 1 mg

30-unit U-100 insulin syringe · Starting dose of its protocol, with 3 ml of water in the 50 mg vial.

What it pairs with

Preparation and dosing

Quick reference

Vial50 mg
Diluent3 ml
Concentration16.67 mg/ml
1 unit =0.167 mg

Preparation

Diluent
Bacteriostatic water

Open calculator →See the guide →

Evidence

Each effect with its evidence level and, where available, its source.

Strong evidence(0)Moderate evidence(0)Early evidence(8)
  • Closes wounds and ulcersExtrapolatedSee study · 1994
  • Firmer, denser skin: more collagenExtrapolatedSee study · 2015
  • Antioxidant: less oxidative stressPreclinicalSee study · 2012
  • Lowers inflammationPreclinicalSee study · 2025
  • Nerve regenerationPreclinicalSee study · 2005
  • Protects the lungPreclinicalSee study · 2022
  • Denser hair, less sheddingExtrapolatedSee study · 2016
  • Cellular longevity: sirtuins and repairPreclinicalSee study · 2018

The science

Mechanisms, studies and references

Copper tripeptide

Safety

It makes sense if you want

  • Skin healing & regeneration
  • Firmer, more radiant skin
  • General body recovery

It does not make sense if

  • Active cancer or oncology treatment in the last 5 years
  • Pregnancy or breastfeeding
  • Wilson disease or copper allergy
  • Severe liver impairment

Talk to your doctor first if this applies (1)

  • Liver disease

The certificate of analysis (CoA) certifies the identity and purity of the batch. It does not certify safety of use.

Verify your batch →

For research use only (RUO). This consult is educational and does not replace your doctor.

Questions

Frequently asked questions

What is it reconstituted with, and how much?

With bacteriostatic water: 3 ml into the 50 mg vial, giving 16.67 mg/ml.

What is the starting dose of the research protocol?

1 → 2 mg, diario. This is the SBL research protocol, with no established clinical regimen in people.

How long is the cycle, and how long does a vial last?

12 weeks ON / 4 weeks OFF. At the starting dose, the 50 mg vial lasts ~4 sem.

Which route is used in research?

Subcutaneous.

When does it make no sense?

It makes no sense with: Active cancer or oncology treatment in the last 5 years, Pregnancy or breastfeeding, Wilson disease or copper allergy, Severe liver impairment. Details in the Safety tab.

What is it combined with?

It goes well with Glutathione. The reasons are in the Protocols tab.

How do I check my batch?

With the code on the vial, in the verifier. The CoA certifies the identity and purity of the batch, not safety of use.

Verify your batch →

See kit

For research use only (RUO). This consult is educational and does not replace your doctor.