PT-141

PT-141

Research peptide

Bremelanotide · MC4R agonist · sexual desire · FDA-approved (2019) · on-demand use

Strong evidence
Molecule approved in United States · 2019What this means ›
🇺🇸 United States · Approved

The molecule is approved as a medicine in United States, under the brand Vyleesi. It was the first approved as-needed injectable of its kind, for hypoactive sexual desire disorder in premenopausal women (FDA, June 2019).

What is approved is the molecule under that pharmaceutical brand. Our vial is research material (RUO).

Source: FDA · Vyleesi (bremelanotide), 21-jun-2019

OverviewProtocolsPreparation and dosingEvidenceSafetyQuestions

Overview

What has it been researched for?

  • More sexual desire Main focusStrong evidence
  • Supports erectionModerate evidence

Research protocols

The SBL research protocol and what the literature reports. Not medical advice.

SBL research protocol · no established clinical regimen in people

Dose
1.5 → 2 mg
Frequency
a demanda · máx 1/24h y 8/mes
Duration
Not available
Route
Subcutaneous
Evidence level
Approved

Tools

Reconstitution calculatorConverts mg to units (U-100), volume and concentration.Open calculator →Preparation (step by step)How to reconstitute, store and handle, with good practice.See the guide →My trackingLog doses, results and notes per goal, in the app.Go to my tracking →

Evidence and studies

See studies →
Strong evidence(1)Moderate evidence(1)Early evidence(0)

Protocols

Research protocols

SBL research protocol · no established clinical regimen in people

Research use, with no established clinical regimen in people.

Dose
1.5 → 2 mg
Frequency
a demanda · máx 1/24h y 8/mes
Timing
a demanda
Duration
Not available
Break
No break
Route
Subcutaneous
Evidence level
Approved

Example dose

05010030
30 u= 1.5 mg

100-unit U-100 insulin syringe · Starting dose of its protocol, with 1 ml of water in the 5 mg vial.

What it pairs with

No pairings are recorded for this vial yet.

Preparation and dosing

Quick reference

Vial5 mg
Diluent1 ml
Concentration5 mg/ml
1 unit =0.05 mg

Preparation

Diluent
Bacteriostatic water

Open calculator →See the guide →

Evidence

Each effect with its evidence level and, where available, its source.

Strong evidence(1)Moderate evidence(1)Early evidence(0)

The science

Mechanisms, studies and references

MC4R agonist

Safety

It makes sense if you want

  • Libido & desire

It does not make sense if

  • Severe heart disease or recent cardiac event
  • Active cancer or oncology treatment in the last 5 years
  • Pregnancy or breastfeeding
  • Cardiovascular disease
  • Uncontrolled hypertension
  • Nitrates for chest pain or angina
  • Sildenafil, tadalafil or another erectile medication

Talk to your doctor first if this applies (4)

  • MAOI antidepressants (phenelzine, tranylcypromine, selegiline)
  • Hypertension
  • Severe liver impairment
  • Severe kidney impairment

The certificate of analysis (CoA) certifies the identity and purity of the batch. It does not certify safety of use.

Verify your batch →

For research use only (RUO). This consult is educational and does not replace your doctor.

Questions

Frequently asked questions

What is it reconstituted with, and how much?

With bacteriostatic water: 1 ml into the 5 mg vial, giving 5 mg/ml.

What is the starting dose of the research protocol?

1.5 → 2 mg, a demanda · máx 1/24h y 8/mes. This is the SBL research protocol, with no established clinical regimen in people.

Which route is used in research?

Subcutaneous.

When does it make no sense?

It makes no sense with: Severe heart disease or recent cardiac event, Active cancer or oncology treatment in the last 5 years, Pregnancy or breastfeeding, Cardiovascular disease, Uncontrolled hypertension, Nitrates for chest pain or angina, Sildenafil, tadalafil or another erectile medication. Details in the Safety tab.

How do I check my batch?

With the code on the vial, in the verifier. The CoA certifies the identity and purity of the batch, not safety of use.

Verify your batch →

See kit

For research use only (RUO). This consult is educational and does not replace your doctor.