TB-500

TB-500 · 10mg

Research peptide

Thymosin β4 fragment · systemic repair, flexibility and antifibrosis

Early evidence
Compounding pharmacies in United States can now prepare it · Oct 2026What this means ›
🇺🇸 United States · Compounding pharmacies may prepare it

Since October 2026, the FDA allows compounding pharmacies in United States to prepare it with a prescription: the step that followed its advisory committee's favourable vote. Next step: the FDA adding it permanently to its list of substances for compounding.

Our vial is research material (RUO), not a pharmacy preparation.

Source: FDA · oct 2026

Overview

What has it been researched for?

  • Repairs tendon, ligament and muscle Main focusEarly evidence
  • Flexibility and less scarringEarly evidence
  • Protects the heartEarly evidence
  • Closes wounds and ulcersEarly evidence
  • Denser hair, less sheddingEarly evidence
  • Protects the retina and the eyeEarly evidence

Research protocols

The SBL research protocol and what the literature reports. Not medical advice.

SBL research protocol · no established clinical regimen in people

Dose
1 mg
Frequency
2×/semana
Duration
8 weeks
Route
Subcutaneous
Evidence level
Preclinical

Tools

Evidence and studies

See studies →

Protocols

Research protocols

SBL research protocol · no established clinical regimen in people

Research use, with no established clinical regimen in people.

Dose
1 mg
Frequency
2×/semana
Timing
cualquier hora
Duration
8 weeks
Break
4 weeks
Route
Subcutaneous
Evidence level
Preclinical

Example dose

0153020
20 u= 1 mg

30-unit U-100 insulin syringe · Starting dose of its protocol, with 2 ml of water in the 10 mg vial.

What it pairs with

Preparation and dosing

Quick reference

Vial10 mg
Diluent2 ml
Concentration5 mg/ml
1 unit =0.05 mg

Preparation

Diluent
Bacteriostatic water

Open calculator →See the guide →

Evidence

Each effect with its evidence level and, where available, its source.

Strong evidence(0)Moderate evidence(0)Early evidence(6)
  • Repairs tendon, ligament and musclePreclinicalSee study · 2026
  • Flexibility and less scarringPreclinicalSee study · 2022
  • Protects the heartPreclinicalSee study · 2004
  • Closes wounds and ulcersExtrapolatedSee study · 2010
  • Denser hair, less sheddingPreclinicalSee study · 2004
  • Protects the retina and the eyeExtrapolatedSee study · 2022

The science

Mechanisms, studies and references

Thymosin β4 fragment

Safety

It makes sense if you want

  • General body recovery
  • Skin healing & regeneration
  • Recover from an injury (tendon, joint)

It does not make sense if

  • Active cancer or oncology treatment in the last 5 years
  • Pregnancy or breastfeeding

Talk to your doctor first if this applies (5)

  • Anticoagulants (warfarin, rivaroxaban, etc.)
  • Autoimmune disease
  • Cardiovascular disease
  • Immunosuppressants
  • Organ or bone-marrow transplant

The certificate of analysis (CoA) certifies the identity and purity of the batch. It does not certify safety of use.

Verify your batch →

For research use only (RUO). This consult is educational and does not replace your doctor.

Questions

Frequently asked questions

What is it reconstituted with, and how much?

With bacteriostatic water: 2 ml into the 10 mg vial, giving 5 mg/ml.

What is the starting dose of the research protocol?

1 mg, 2×/semana. This is the SBL research protocol, with no established clinical regimen in people.

How long is the cycle, and how long does a vial last?

8 weeks ON / 4 weeks OFF. At the starting dose, the 10 mg vial lasts ~5 sem.

Which route is used in research?

Subcutaneous.

When does it make no sense?

It makes no sense with: Active cancer or oncology treatment in the last 5 years, Pregnancy or breastfeeding. Details in the Safety tab.

How do I check my batch?

With the code on the vial, in the verifier. The CoA certifies the identity and purity of the batch, not safety of use.

Verify your batch →

See kit

For research use only (RUO). This consult is educational and does not replace your doctor.