Weekly amylin analog · satiety by another route · the other half of CagriSema, under FDA review
The ReferenceBenefits, protocols and preparationOpen the reference →The hormone that travels with insulin, in a weekly version.
Activates amylin and calcitonin receptors in the brain.
You feel full on less food.
Slows gastric emptying and flattens post-meal glucose.
Complementary pathway: the effect stacks.
Peptides often synergize. These are the most studied combinations with this product, and what outcome they target.
Any combination must respect each peptide's protocol. If you have doubts about dosing or timing, message us before starting.
Cagrilintide is a long-acting amylin analog. Amylin leaves the pancreas together with insulin and tells the brain you have eaten: it slows stomach emptying and brings satiety forward.
SuperBio Labs Cagrilintide is supplied as lyophilized powder with HPLC purity ≥99%, with a Certificate of Analysis per lot.
It works through a different pathway from GLP-1s, which is why it was studied with semaglutide. In REDEFINE 1 (3,417 adults, 68 weeks), on its own it lowered weight 11.5% and with semaglutide 20.4%, versus 14.9% for semaglutide alone and 3.0% for placebo (11.8%, 22.7%, 16.1% and 2.3% in those who stayed on treatment). In type 2 diabetes the combination lost 13.7% (REDEFINE 2). Against tirzepatide (REDEFINE 4, 84 weeks, open-label) the combination lost 20.2% vs 23.6% and did not reach non-inferiority. The FDA has been reviewing CagriSema since 18 December 2025; Novo Nordisk guides to a decision in late 2026.
Informed professional research use only.
We don't just hand you the vial. Every Cagrilintide purchase includes everything you need to apply it safely, with a clear protocol and our team available 24/7.
Lyophilized · HPLC purity ≥99% · Batch with COA
Sterile diluent · 0.9% benzyl alcohol
21G needle · For peptide reconstitution
30 units · daily · 30-day cap
1 per application + 1 to reconstitute
Free app · Week-by-week protocol, product sheet and usage guide
8 steps · From opening the kit to application
App · Tracking · Human team 24/7
About supplies: the quantity of syringes and wipes adjusts automatically based on the presentation you choose. For extended cycles (Cagrilintide, GHK-Cu and similar) we cap supplies at 30 days — beyond that, 29G insulin syringes and 70% alcohol wipes are pharmacy items available without prescription in any city.
This product meets all five — your batch COA ships with the kit.
The official protocol included in the kit. If you have pre-existing medical conditions, consult a professional before starting.
Wk 1–4: 250 mcg → Wk 5–8: 500 mcg → Wk 9–12: 1 mg → Wk 13–16: 1.7 mg → Wk 17–20: 2.4 mg
Combine with TB-500 for accelerated recovery. Local application recommended.
The studied pairing: amylin + GLP-1.
Early satiety · eat less without a fight.
Lower the GLP-1 and add amylin.
Flatter spikes.
Hold the weight lost · explored in trials.
The digestive profile of its class. Nausea, constipation and vomiting are the most common, mostly during dose escalation. With semaglutide in REDEFINE 1: nausea 55%, constipation 31%, vomiting 26% (placebo 13%, 12% and 4%).
Alone it is milder than the combination. Discontinuations due to adverse events with the combination: 5.9% (placebo 3.5%). Others: fatigue, reflux. In type 2 diabetes (REDEFINE 2) discontinuations due to adverse events were 8.4% versus 3% on placebo. Two class notices: if you are having surgery or an endoscopy under sedation, say you use this kind of compound (slow gastric emptying; FDA label, Nov 2024). If you vomit or have diarrhea, hydrate: dehydration can harm the kidney. Do not use in pregnancy or with prior pancreatitis. If you already use a GLP-1, that pairing is what was studied, but add it with guidance.
| CAS number | 1415456-99-3 |
| Molecular weight | ≈4409 Da |
| Class | Long-acting amylin analog |
| Purity (HPLC) | ≥99% |
| Format | Lyophilized powder |
| Quantity | 10 mg per vial |
| Endotoxins | <1.0 EU/mg |
| Storage | −20 °C, protected from light |
| Clinical reference | REDEFINE 1 (NEJM 2025) |
| Use | Use under professional judgment |