Recovery · Body Protection

Cagrilintide 10mg

Weekly amylin analog · satiety by another route · the other half of CagriSema, under FDA review

The ReferenceBenefits, protocols and preparationOpen the reference →
Purity
≥99%
Format
10mg
Length
15 AA
MW
1419
Phase 3 complete · under review in United States since Dec 2025What this means ›
🇺🇸 United States · Under review

The approval application has been filed and is under review in United States (CagriSema (con semaglutida)). Novo Nordisk developed cagrilintide to be used with semaglutide (CagriSema). In REDEFINE 1 (3,417 adults, 68 weeks) the combination reached 22.7% weight loss and cagrilintide alone 11.8%, versus 2.3% on placebo (all participants: 20.4%, 11.5% and 3.0%). In type 2 diabetes (REDEFINE 2) the combination lost 13.7%. Against tirzepatide (REDEFINE 4, February 2026) it lost 20.2% vs 23.6% and did not reach non-inferiority; the application remains under review and Novo Nordisk guides to a decision in late 2026. Cagrilintide alone entered its own phase 3 programme (RENEW) in late 2025, with no results yet. The FDA application was filed on December 18, 2025. Next step: the FDA's decision.

Being under review is not being approved. Today it remains an investigational compound.

Source: FDA · solicitud de CagriSema, 18-dic-2025 · Novo Nordisk · REDEFINE 1 (NEJM 2025), REDEFINE 2 (NEJM 2025), REDEFINE 4 (23-feb-2026)

For research use only (RUO) Ships from Quito · EC 1-3 days · LATAM 4-10 Arrives damaged? We replace it free COA per batch
CAS · 137525-51-0 MW · 1419.55 Da Stock · Available
How it works

4 mechanisms. Another route to satiety.

The hormone that travels with insulin, in a weekly version.

Amylin receptor

Activates amylin and calcitonin receptors in the brain.

Early satiety

You feel full on less food.

Slower stomach

Slows gastric emptying and flattens post-meal glucose.

Adds to GLP-1

Complementary pathway: the effect stacks.

Recommended stacks

Stacks. What to pair it with.

Peptides often synergize. These are the most studied combinations with this product, and what outcome they target.

Any combination must respect each peptide's protocol. If you have doubts about dosing or timing, message us before starting.

The compound

Technical description.

Cagrilintide is a long-acting amylin analog. Amylin leaves the pancreas together with insulin and tells the brain you have eaten: it slows stomach emptying and brings satiety forward.

SuperBio Labs Cagrilintide is supplied as lyophilized powder with HPLC purity ≥99%, with a Certificate of Analysis per lot.

It works through a different pathway from GLP-1s, which is why it was studied with semaglutide. In REDEFINE 1 (3,417 adults, 68 weeks), on its own it lowered weight 11.5% and with semaglutide 20.4%, versus 14.9% for semaglutide alone and 3.0% for placebo (11.8%, 22.7%, 16.1% and 2.3% in those who stayed on treatment). In type 2 diabetes the combination lost 13.7% (REDEFINE 2). Against tirzepatide (REDEFINE 4, 84 weeks, open-label) the combination lost 20.2% vs 23.6% and did not reach non-inferiority. The FDA has been reviewing CagriSema since 18 December 2025; Novo Nordisk guides to a decision in late 2026.

Informed professional research use only.

Your complete kit, ready to apply.

We don't just hand you the vial. Every Cagrilintide purchase includes everything you need to apply it safely, with a clear protocol and our team available 24/7.

Cagrilintide vial

Lyophilized · HPLC purity ≥99% · Batch with COA

BAC

Bacteriostatic water 30ml

Sterile diluent · 0.9% benzyl alcohol

3ml

1 extraction syringe 3ml

21G needle · For peptide reconstitution

30 insulin syringes (29G)

30 units · daily · 30-day cap

70%

31 alcohol wipes 70%

1 per application + 1 to reconstitute

Your protocol and product sheet, in the app

Free app · Week-by-week protocol, product sheet and usage guide

Visual step-by-step guide

8 steps · From opening the kit to application

SuperBio OS · Support

App · Tracking · Human team 24/7

About supplies: the quantity of syringes and wipes adjusts automatically based on the presentation you choose. For extended cycles (Cagrilintide, GHK-Cu and similar) we cap supplies at 30 days — beyond that, 29G insulin syringes and 70% alcohol wipes are pharmacy items available without prescription in any city.

Before you buy · from any store

How to choose where to buy peptides.

01
Per-batch, verifiable COA The certificate exists and can be checked — not "available on request".
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02
HPLC purity + LC-MS identity How much is in the vial, and that it is the right peptide.
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03
Endotoxins tested LAL test within range — not just purity.
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04
2-8°C cold chain Documented end to end, not promised.
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05
Traceability and support Lot number on the vial and someone who answers after.

This product meets all five — your batch COA ships with the kit.

Recommended application protocol.

The official protocol included in the kit. If you have pre-existing medical conditions, consult a professional before starting.

Reconstitution
2 ml of bacteriostatic water → 5 mg/ml
Starting dose
250 mcg
Target dose
0.25 → 2.4 mg
Frequency
1×/week
Cycle duration
20 weeks
Application site
Subcutaneous · close to affected area for localization
Storage (reconstituted)
60 days refrigerated (2–8°C)

Recommended titration

Wk 1–4: 250 mcg → Wk 5–8: 500 mcg → Wk 9–12: 1 mg → Wk 13–16: 1.7 mg → Wk 17–20: 2.4 mg

Note

Combine with TB-500 for accelerated recovery. Local application recommended.

When to use Cagrilintide.

Plateau on a GLP-1

The studied pairing: amylin + GLP-1.

Emotional hunger

Early satiety · eat less without a fight.

Intolerance to high GLP-1 doses

Lower the GLP-1 and add amylin.

Post-meal glucose

Flatter spikes.

Maintenance

Hold the weight lost · explored in trials.

Honest side effects.

The digestive profile of its class. Nausea, constipation and vomiting are the most common, mostly during dose escalation. With semaglutide in REDEFINE 1: nausea 55%, constipation 31%, vomiting 26% (placebo 13%, 12% and 4%).

Alone it is milder than the combination. Discontinuations due to adverse events with the combination: 5.9% (placebo 3.5%). Others: fatigue, reflux. In type 2 diabetes (REDEFINE 2) discontinuations due to adverse events were 8.4% versus 3% on placebo. Two class notices: if you are having surgery or an endoscopy under sedation, say you use this kind of compound (slow gastric emptying; FDA label, Nov 2024). If you vomit or have diarrhea, hydrate: dehydration can harm the kidney. Do not use in pregnancy or with prior pancreatitis. If you already use a GLP-1, that pairing is what was studied, but add it with guidance.

Technical specifications

CAS number1415456-99-3
Molecular weight≈4409 Da
ClassLong-acting amylin analog
Purity (HPLC)≥99%
FormatLyophilized powder
Quantity10 mg per vial
Endotoxins<1.0 EU/mg
Storage−20 °C, protected from light
Clinical referenceREDEFINE 1 (NEJM 2025)
UseUse under professional judgment

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