Blend · Longevity · Top Seller

CALM SKIN 60mg

GHK-Cu + KPV · Skin and calm · collagen with an anti-inflammatory brake

Purity
≥99%
Total
60mg
Components
2
Frequency
daily
Its actives, backed by the FDA advisory committeeWhat this means ›

It is a premix: it has no regulatory file of its own. What does have a track record are its actives — KPV. In July 2026 the FDA pharmacy compounding advisory committee voted in favor of adding it to the 503A list — the substances US compounding pharmacies may use. Of the seven peptides reviewed, six passed — and all six are in our catalog.

Note: It is a committee recommendation, not an approval: it is not binding on the FDA and formal rulemaking is still pending, which usually takes a year or more. FDA staff had recommended rejecting them.

Source: FDA · Pharmacy Compounding Advisory Committee, 23-24 jul 2026

For research use only (RUO) Ships from Quito · EC 1-3 days · LATAM 4-10 Arrives damaged? We replace it free COA per batch
Type · Pre-mixed blend Components · 2 peptides Stock · Available
How it works

2 actives. One single vial.

One reprograms the tissue and the other switches off the inflammation that wears it down. This is what each one does at the cellular level, in plain language.

GHK-Cu · 50mg

Modulates the expression of 4,192 genes toward a young-tissue profile. +302% collagen in skin fibroblasts.

KPV · 10mg

Tripeptide derived from α-MSH. Lowers inflammatory signalling through the NF-κB pathway without shutting down the immune response.

For reactive skin

Redness, flare-ups and skin that reacts to everything: that is where KPV changes the outcome GHK alone cannot reach.

Rebuild and calm

GHK gives the instruction to rebuild; KPV removes the inflammatory noise that interrupts it.

Recommended combinations

Combine with.

CALM SKIN alone is complete for most people. When you want to reach the next level:

Any combination must respect the protocol of each peptide. If you have questions about dose or timing, write to us before starting.

The compound

Technical description.

CALM SKIN brings together the two peptides that work on skin from different angles: GHK-Cu, which reprograms tissue gene expression toward a younger profile, and KPV, a tripeptide derived from the C-terminal end of α-MSH with anti-inflammatory action. It is the blend for reactive skin — the kind that not only ages, but flares.

Every component ships with ≥99% HPLC purity and a per-batch Certificate of Analysis covering LC-MS identity, peptide content (98–102% per component), endotoxin levels (<1.0 EU/mg) and residual solvents.

The ratio favours GHK (50 of the 60 mg) because its effective doses are in milligrams, while KPV works in smaller amounts. GHK-Cu modulates the expression of 4,192 genes toward a young-tissue profile and shows +302% collagen in skin fibroblasts; KPV lowers inflammatory signalling through the NF-κB pathway. One rebuilds and the other switches off what prevents rebuilding.

Product for informed professional use.

Your complete kit, ready to apply.

Every CALM SKIN purchase includes everything you need to apply it safely.

Complete CALM SKIN kit · 8 components
Reference image

CALM SKIN 60mg vial

Lyophilized blend · GHK + KPV · HPLC ≥99%

BAC

Bacteriostatic water 30ml

Sterile solvent

3ml extraction syringe

21G needle · For reconstitution

30 insulin syringes

One per application · 30 days

70%

31 alcohol wipes 70%

1 per application + 1 to reconstitute

Your protocol and product sheet, in the app

Free app · Week-by-week protocol, product sheet and usage guide

8-step visual guide

From opening the kit to first application

SuperBio OS

App · Cycle tracking · 24/7 support

About the supplies: quantity calibrated to the loading protocol (5×/week × 4 weeks) + maintenance (3×/week × 2 weeks) = 26-30 applications over 6 weeks.

Before you buy · from any store

How to choose where to buy peptides.

01
Per-batch, verifiable COA The certificate exists and can be checked — not "available on request".
02
HPLC purity + LC-MS identity How much is in the vial, and that it is the right peptide.
03
Endotoxins tested LAL test within range — not just purity.
04
2-8°C cold chain Documented end to end, not promised.
05
Traceability and support Lot number on the vial and someone who answers after.

This product meets all five — your batch COA ships with the kit.

Recommended application protocol.

Conservative protocol that we deliver in the kit, printed and digital. If you have pre-existing medical conditions, consult a professional before starting.

Reconstitution
2 ml of bacteriostatic water → 30 mg/ml
Standard dose
1.2 → 2.1 mg
U-100 units
4 → 6 → 7 u
Frequency
daily
Cycle duration
12 weeks ON / 4 weeks OFF
Application site
Subcutaneous · abdomen
Storage (reconstituted)
30 days refrigerated (2–8°C)
Tip

GHK-Cu gives the solution a faint blue tone (it's the copper chelation). It's normal and expected — it confirms GHK is present.

If copper stings you

Copper (GHK-Cu) is one of the peptides that stings the most on application, and in some people the soreness lasts more than a day. It's normal. Here's how it hurts less — these are application-comfort tips, not medical advice.

01

More bacteriostatic water

Reconstituting with more water lowers the concentration and with it the sting. The lever that helps most ★

02

Room temperature

Take the vial out of the fridge 10–15 min before: cold liquid stings more.

03

Inject slowly

Push the liquid in slowly, 10–15 seconds, not all at once.

04

Pick the site better

The upper glute tends to hurt less than the abdomen: fewer surface nerves and more fat.

05

Hydrate first

2 glasses of water ~30 min before: hydrated tissue disperses the liquid better and hurts less.

Rotate between days, don't split the dose. Change the site between applications. Splitting one dose into two injections leaves you with two sore spots instead of one.

Your part counts too: good hydration and anti-inflammatory habits (omega-3, turmeric, real food) help the area recover better.

If the soreness is intense, with growing swelling, heat or fever, that's no longer comfort: consult a health professional.

What to expect · real timeline.

Based on GHK-Cu clinical literature (Pickart) and KPV studies. Your experience varies with physiology.

Week 1–2
Visible skin hydration · less dryness · immediate GHK-Cu effect.
Week 3–4
Improved texture · pores less visible · first collagen response.
Week 4–6
Noticeable firmness · fine lines reduced · physical recovery evident · scars fading.
Week 6–8
Peak results · visibly younger skin · scars faded · lesions resolved.

Honest side effects.

Good safety profile. Both components have a solid track record in research:

Mild redness at the injection site (resolves within an hour) · stinging on application, from the copper · mild drowsiness in the first week.

Copper: do not use it on the same day or with the same syringe as glutathione — copper oxidises it. And do not stack it with Glow or Klow: both already contain GHK-Cu.

Wilson disease: because of the copper, it is not recommended for people with Wilson disease or copper allergy.

Technical specifications

ComponentsGHK-Cu 50mg + KPV 10mg
Total peptide60mg lyophilized
Purity (HPLC)≥99% per component
FormatPre-mixed lyophilized powder
COAPer batch · independent laboratory
Endotoxins<1.0 EU/mg (LAL test)
Storage (unreconstituted)2–8 °C, protected from light · 24 months
Storage (reconstituted)2–8 °C · 30 days
UseUse under professional judgment

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