Hormonal · GHRH · GH/IGF-1 axis

Tesamorelin 20mg

FDA-approved GHRH analog · visceral fat and growth hormone axis

Purity
≥99%
Format
20mg
Class
GHRH
Axis
GH/IGF-1
For research use only (RUO) Ships from Quito · EC 1-3 days · LATAM 4-10 Arrives damaged? We replace it free COA per batch
CAS · 218949-48-5 MW · 5135.9 Da Stock · Available
How it works

4 mechanisms. Physiological GH axis.

Tesamorelin is a stabilized GHRH analog (44 aa) — the only growth hormone secretagogue approved by the FDA (Egrifta). It stimulates your own GH in a pulsatile way, preserving natural IGF-1 feedback.

Visceral fat ↓

Its FDA-approved flagship use: reduces visceral abdominal fat (−15–18% VAT in trials) — the fat that wraps around your organs.

Physiological GH/IGF-1

Raises GH and IGF-1 pulsatilely, not flat. Preserves IGF-1 feedback, unlike exogenous growth hormone.

Liver and composition

Reduces hepatic fat (signal in NAFLD) and provides a modest improvement in lean mass and body composition.

Cognition and sleep

A trial in older adults showed better executive function. Nocturnal GHRH also supports sleep quality.

Recommended combinations

Combine with.

Tesamorelin pairs well with metabolic and recovery pathways different from its own. Never with CJC-1295 (dual GHRH, redundant).

If you have pre-diabetes or diabetes, monitor glucose and insulin — Tesamorelin can raise them. Consult your physician before combining.

The compound

Technical description.

Tesamorelin is a stabilized synthetic analog of GHRH (growth hormone–releasing hormone, 44 amino acids) and is the only FDA-approved GH secretagogue (brand name Egrifta). Instead of injecting growth hormone directly, it asks your own pituitary to release it — pulsatilely and preserving natural IGF-1 feedback.

SuperBio Labs Tesamorelin is supplied as lyophilized powder with verified HPLC ≥99% purity. Each lot ships with an independent Certificate of Analysis confirming identity by LC-MS, peptide content (98–102%), and endotoxin levels (<1.0 EU/mg).

Its flagship lane, with high evidence (phase III trials in ~816 patients), is the reduction of visceral abdominal fat (−15–18% VAT). Beyond that, there are signals in hepatic fat/NAFLD (Lancet HIV 2019) and in executive function in older adults (Arch Neurol 2012). In body composition the lean-mass contribution is modest — this is not a peptide for building muscle. Honest caveat: much of the evidence comes from specific populations (HIV and older adults).

Within our catalog, Tesamorelin holds the GH-axis slot: it gains credibility (FDA) and a lane of its own (visceral fat), but it does not build muscle nor provide the ghrelin/sleep arm of an Ipamorelin.

Informed professional research use only.

Complete kit · ready to reconstitute.

Each order includes everything needed for the cycle. No separate purchases required.

Vial + BWFI + syringes + alcohol swabs · kit contents
lyophilized Tesamorelin 20mg vial
BWFI 2ml vial (bacteriostatic water)
30× insulin syringes U-100 0.5ml 29G
60× alcohol swabs (pre + post)
cycle organizer box
printed reconstitution guide
nighttime application protocol
batch COA (digital + printed)
Before you buy · from any store

How to choose where to buy peptides.

01
Per-batch, verifiable COA The certificate exists and can be checked — not "available on request".
02
HPLC purity + LC-MS identity How much is in the vial, and that it is the right peptide.
03
Endotoxins tested LAL test within range — not just purity.
04
2-8°C cold chain Documented end to end, not promised.
05
Traceability and support Lot number on the vial and someone who answers after.

This product meets all five — your batch COA ships with the kit.

Recommended application protocol.

Conservative protocol included in the kit. If you have pre-diabetes, diabetes, or raised IGF-1, consult your physician before starting.

Reconstitution
2 ml bacteriostatic water → 10 mg/ml
Standard dose
1–2 mg/day (FDA 2 mg; community/cognition 1 mg)
U-100 units (1mg)
10 units
Frequency
Daily
Best timing
Night, fasted (respects the nocturnal GH pulse)
Cycle length
ON ~3 months / OFF ~2 months
Combine with
Tirz, MOTS-c · never with CJC-1295 (dual GHRH)
Storage (reconstituted)
30 days refrigerated (2–8°C)

When to use Tesamorelin.

Visceral fat

Abdominal/visceral adiposity · FDA-approved flagship use.

GH/IGF-1 axis

Raise GH and IGF-1 physiologically and pulsatilely, without exogenous GH.

Fatty liver

NAFLD · signal of reduced hepatic fat in trials.

Composition with GLP-1

Preserve lean mass during weight loss (not glucose).

Cognition

Executive function in older adults · real trial.

Sleep

Nocturnal GHRH · supports deep-sleep quality.

Honest side effects.

Generally well tolerated, but with clear monitoring. This is not a harmless peptide: it has real contraindications.

It raises IGF-1 (monitor with labs) and can raise glucose/insulin — caution in pre-diabetes and diabetes. It may cause fluid retention and arthralgia (joint pain). Contraindicated in active cancer, pituitary disease, and pregnancy. For athletes: it is on the WADA list (S2.2.4). Never combine it with CJC-1295 (both are GHRH).

Technical specifications

ProductTesamorelin
CAS Number218949-48-5
Molecular Weight5135.9 Da
Purity (HPLC)≥99%
FormatLyophilized powder
Quantity20mg per vial
ClassGHRH analog (44 aa)
Endotoxins<1.0 EU/mg
Storage−20 °C, protected from light
UseUse under professional judgment

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