KPV

KPV

Research peptide

Calms gut and skin inflammation

Early evidence
Compounding pharmacies in United States can now prepare it · Oct 2026What this means ›
🇺🇸 United States · Compounding pharmacies may prepare it

Since October 2026, the FDA allows compounding pharmacies in United States to prepare it with a prescription: the step that followed its advisory committee's favourable vote. Next step: the FDA adding it permanently to its list of substances for compounding.

Our vial is research material (RUO), not a pharmacy preparation.

Source: FDA · oct 2026

Overview

What has it been researched for?

  • Protects and repairs the gut lining Main focusEarly evidence
  • Calms gut inflammationEarly evidence
  • Closes wounds and ulcersEarly evidence
  • Lowers inflammationEarly evidence
  • Calms reactive, irritated skinEarly evidence
  • Antimicrobial action on skin and mucosaEarly evidence

Research protocols

The SBL research protocol and what the literature reports. Not medical advice.

SBL research protocol · no established clinical regimen in people

Dose
500 mcg
Frequency
5-on / 2-off
Duration
6 weeks
Route
Subcutaneous (oral para el intestino)
Evidence level
Preclinical

Tools

Evidence and studies

See studies →

Protocols

Research protocols

SBL research protocol · no established clinical regimen in people

Research use, with no established clinical regimen in people.

Dose
500 mcg
Frequency
5-on / 2-off
Timing
cualquier hora
Duration
6 weeks
Break
2 weeks
Route
Subcutaneous (oral para el intestino)
Evidence level
Preclinical

Example dose

0153010
10 u= 0.5 mg

30-unit U-100 insulin syringe · Starting dose of its protocol, with 1 ml of water in the 5 mg vial.

What it pairs with

  • BPC-157 For the gut they go together: KPV calms inflammation and BPC-157 repairs the lining; the barrier comes first (ISSCA course, class 2.1).

Preparation and dosing

Quick reference

Vial5 mg
Diluent1 ml
Concentration5 mg/ml
1 unit =0.05 mg

Preparation

Diluent
Bacteriostatic water

Open calculator →See the guide →

Evidence

Each effect with its evidence level and, where available, its source.

Strong evidence(0)Moderate evidence(0)Early evidence(6)
  • Protects and repairs the gut liningPreclinicalSee study · 2017
  • Calms gut inflammationPreclinicalSee study · 2008
  • Closes wounds and ulcersPreclinicalSee study · 2006
  • Lowers inflammationPreclinicalSee study · 2007
  • Calms reactive, irritated skinPreclinicalSee study · 2004
  • Antimicrobial action on skin and mucosaPreclinicalSee study · 2000

The science

Mechanisms, studies and references

α-MSH tripeptide

Safety

It makes sense if you want

  • Gut health & digestion
  • Skin healing & regeneration
  • Boost my immunity

It does not make sense if

  • Active cancer or oncology treatment in the last 5 years
  • Pregnancy or breastfeeding

Talk to your doctor first if this applies (3)

  • Autoimmune disease
  • Immunosuppressants
  • Organ or bone-marrow transplant

The certificate of analysis (CoA) certifies the identity and purity of the batch. It does not certify safety of use.

Verify your batch →

For research use only (RUO). This consult is educational and does not replace your doctor.

Questions

Frequently asked questions

What is it reconstituted with, and how much?

With bacteriostatic water: 1 ml into the 5 mg vial, giving 5 mg/ml.

What is the starting dose of the research protocol?

500 mcg, 5-on / 2-off. This is the SBL research protocol, with no established clinical regimen in people.

How long is the cycle, and how long does a vial last?

6 weeks ON / 2 weeks OFF. At the starting dose, the 5 mg vial lasts ~2 sem.

Which route is used in research?

Subcutaneous (oral para el intestino).

When does it make no sense?

It makes no sense with: Active cancer or oncology treatment in the last 5 years, Pregnancy or breastfeeding. Details in the Safety tab.

What is it combined with?

It goes well with BPC-157. The reasons are in the Protocols tab.

How do I check my batch?

With the code on the vial, in the verifier. The CoA certifies the identity and purity of the batch, not safety of use.

Verify your batch →

See kit

For research use only (RUO). This consult is educational and does not replace your doctor.