Semax

Semax · 10mg

Research peptide

Focus, memory and brain recovery · approved in Russia

Moderate evidence
Registered medicine in Russia · pharmacies in United States can now prepare itWhat this means ›
🇷🇺 Russia · Registered medicine🇺🇸 United States · Compounding pharmacies may prepare it

It is a registered medicine in Russia, under the brand Semax. Since October 2026, the FDA allows compounding pharmacies in United States to prepare it with a prescription: the step that followed its advisory committee's favourable vote.

What is registered is that brand's medicine in that country. Our vial is research material (RUO).

Overview

What has it been researched for?

  • Attention, memory and less mental fatigue Main focusEarly evidence
  • Neuroprotection: raises BDNFModerate evidence
  • Protects the retina and the eyeModerate evidence
  • Better mood and less stressEarly evidence

Research protocols

The SBL research protocol and what the literature reports. Not medical advice.

SBL research protocol · no established clinical regimen in people

Dose
400 mcg
Frequency
2×/día
Duration
4 weeks
Route
Intranasal
Evidence level
Human pilot

Tools

Evidence and studies

See studies →

Protocols

Research protocols

SBL research protocol · no established clinical regimen in people

Research use, with no established clinical regimen in people.

Dose
400 mcg
Frequency
2×/día
Timing
mañana y primera tarde
Duration
4 weeks
Break
2 weeks
Route
Intranasal
Evidence level
Human pilot

Example dose

400 mcg

It is a nasal spray: it is counted in puffs, not units.

What it pairs with

No pairings are recorded for this vial yet.

Preparation and dosing

Quick reference

Vial10 mg
Diluent3 ml
Concentration3.33 mg/ml
1 unit =—

Preparation

Diluent
0.9 % saline

Open calculator →See the guide →

Evidence

Each effect with its evidence level and, where available, its source.

Strong evidence(0)Moderate evidence(2)Early evidence(2)
  • Attention, memory and less mental fatiguePreclinicalSee study · 1997
  • Neuroprotection: raises BDNFHuman pilotSee study · 2018
  • Protects the retina and the eyeHuman pilotSee study · 2000
  • Better mood and less stressPreclinicalSee study · 2024

The science

Mechanisms, studies and references

ACTH analog · BDNF

Safety

It makes sense if you want

  • More focus & memory
  • Calm, mood & less anxiety
  • Longevity & deep anti-aging

It does not make sense if

  • Active cancer or oncology treatment in the last 5 years
  • Pregnancy or breastfeeding

Talk to your doctor first if this applies (7)

  • Antidepressants / anxiolytics
  • MAOI antidepressants (phenelzine, tranylcypromine, selegiline)
  • Depression or anxiety
  • Type 2 diabetes / prediabetes
  • Cardiovascular disease
  • Stimulants or dopaminergic medication (methylphenidate, amphetamines, levodopa)
  • Hypertension

The certificate of analysis (CoA) certifies the identity and purity of the batch. It does not certify safety of use.

Verify your batch →

For research use only (RUO). This consult is educational and does not replace your doctor.

Questions

Frequently asked questions

What is it reconstituted with, and how much?

With 0.9 % saline: 3 ml into the 10 mg vial, giving 3.33 mg/ml.

What is the starting dose of the research protocol?

400 mcg, 2×/día. This is the SBL research protocol, with no established clinical regimen in people.

How long is the cycle, and how long does a vial last?

4 weeks ON / 2 weeks OFF. At the starting dose, the 10 mg vial lasts ~1.8 sem.

Which route is used in research?

Intranasal.

When does it make no sense?

It makes no sense with: Active cancer or oncology treatment in the last 5 years, Pregnancy or breastfeeding. Details in the Safety tab.

How do I check my batch?

With the code on the vial, in the verifier. The CoA certifies the identity and purity of the batch, not safety of use.

Verify your batch →

See kit

For research use only (RUO). This consult is educational and does not replace your doctor.