Cognitive · Nootropic · BDNF

Semax 30mg

ACTH(4-10) analog heptapeptide · Russian nootropic · neuroplasticity

Purity
≥99%
Format
30mg
Length
7 AA
Cycle
2-4 wk
For research use only (RUO) Ships from Quito · EC 1-3 days · LATAM 4-10 Arrives damaged? We replace it free COA per batch
CAS · 80714-61-0 MW · 813.92 Da Stock · Available
How it works

4 mechanisms. Russian origin, clinical validation.

Semax was developed at the Russian Academy of Sciences in the 1980s. It is part of the Russian medical formulary for ischemic stroke. 40+ years of clinical use.

BDNF + NGF ↑

Increases Brain-Derived Neurotrophic Factor and NGF within hours. It is the fastest and most selective BDNF activator documented in the nootropic literature.

Deep focus

Modulates dopamine and serotonin without stimulating cortisol. Subjective effect: "clean" focus without the typical tension of caffeine or stimulants.

Memory + learning

Improves working memory and long-term learning consolidation. Documented in Russian studies for students and high-demand professionals.

Neuroprotection

Reduces oxidative neural damage. Used in Russian protocols after mild stroke and head trauma. Antioxidant action specific to brain tissue.

Recommended combinations

Combine with.

Semax is a powerful standalone nootropic. Combining it with longevity or metabolic peptides amplifies the cognitive reset.

Any combination must respect the protocol for each peptide. If you have questions, write to us before you start.

The compound

Technical description.

Semax is a synthetic heptapeptide (Met-Glu-His-Phe-Pro-Gly-Pro) analog of the ACTH(4-10) fragment — the non-steroidal portion of adrenocorticotropic hormone. It was developed at the Institute of Molecular Genetics of the Russian Academy of Sciences in the 1980s and has been part of the Russian medical formulary since 1996 (for ischemic stroke and cognitive disorders).

SuperBio Labs Semax is supplied as lyophilized powder with verified HPLC purity ≥99%. Each lot ships with an independent Certificate of Analysis confirming identity by LC-MS, peptide content (98–102%), and endotoxin levels (<1.0 EU/mg).

Unlike classic stimulants (caffeine, modafinil), Semax does not raise cortisol and does not produce rapid tolerance. Its dual mechanism — increased BDNF/NGF + dopaminergic modulation — produces a state of deep, clean focus with lasting benefits to memory and plasticity. It is one of the most widely used nootropics among high-demand professionals (surgeons, traders, engineers) in the European biohacker community since the mid-2010s.

Producto para uso profesional informado.

Complete kit · ready to reconstitute.

Every order includes everything needed for the cycle. Nothing to buy separately.

Vial + BWFI + syringes + alcohol swabs · kit contents
lyophilized Semax 30mg vial
BWFI 3ml vial (bacteriostatic water)
15× U-100 insulin syringes 0.5ml 29G
30× alcohol swabs (pre + post)
cycle organizer box
printed reconstitution guide
SC + nasal application protocol
lot COA (digital + printed)
Before you buy · from any store

How to choose where to buy peptides.

01
Per-batch, verifiable COA The certificate exists and can be checked — not "available on request".
02
HPLC purity + LC-MS identity How much is in the vial, and that it is the right peptide.
03
Endotoxins tested LAL test within range — not just purity.
04
2-8°C cold chain Documented end to end, not promised.
05
Traceability and support Lot number on the vial and someone who answers after.

This product meets all five — your batch COA ships with the kit.

Recommended application protocol.

Semax allows two routes: nasal (most common in Russia) or subcutaneous. Both are valid — the dose is adjusted depending on the route.

Reconstitution
3 ml of bacteriostatic water → 10 mg/ml
Nasal dose
100–600 mcg/day (1–6 drops)
Subcutaneous dose
0.5–1 mg/day
U-100 units (1mg SC)
10 units
Frequency
1–2×/day · morning and midday
Cycle duration
2–4 weeks · 2-week break
Best time
Morning on an empty stomach · avoid after 4:00 PM
Storage (reconstituted)
30 days refrigerated (2–8°C)
Important

Do not administer after 4:00 PM — it may interfere with sleep onset in sensitive individuals. If used nasally, alternate nostrils between doses to avoid local irritation.

What to expect · real timeline.

2-4 week cycle with cognitive response from day 1.

Day 1–3
Noticeable focus. A sense of mental clarity and clean energy 30-60 minutes post-dose.
Day 4–10
Memory and learning · improved retention · 6+ hours of intense work capacity without mental fatigue.
Day 11–28
Consolidated neuroplasticity · stable mood · noticeable stress resilience · sleep unaffected if the AM schedule is respected.
Post-cycle
Benefits persist 2-4 weeks · no sharp crash · no withdrawal syndrome · 2-week break between cycles.

When to use Semax.

High-demand professionals

Surgeons, traders, engineers · 6-8 hours of deep focus · no caffeine peak-and-crash.

Students during exams

Improved memory consolidation · long-term retention · 2-4 week cycle for exam season.

Cognitive recovery

Post-burnout · chronic brain fog · post-COVID mental fatigue · BDNF reset.

Adult ADHD

Focus without adrenergic stimulation · no tolerance · biohacker-community alternative to methylphenidate.

Mild stroke / TBI

Documented in Russian post-stroke protocols · neuroprotection · language and memory recovery.

Performance anxiety

Modulates dopamine without raising cortisol · subtle anxiolytic effect · useful before presentations or exams.

Honest side effects.

Very well tolerated. Excellent safety profile over 40+ years of Russian clinical use:

If used nasally: local irritation of the nasal mucosa (alternate nostrils, use divided dosing) · occasional nasal dryness · sneezing on first application · mild stimulation if applied late (avoid after 4:00 PM) · no documented increase in blood pressure · no tolerance development when cycles are respected (2-4 weeks + 2-week break).

Technical specifications

ProductSemax (ACTH(4-10) analog)
CAS Number80714-61-0
Molecular Weight813.92 Da
SequenceMet-Glu-His-Phe-Pro-Gly-Pro
Purity (HPLC)≥99%
FormatLyophilized powder
Quantity30mg per vial
OriginRussian Academy of Sciences (Institute of Molecular Genetics)
Endotoxins<1.0 EU/mg
Storage−20 °C, protected from light
UseUso bajo criterio profesional

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