Longevity · Redox coenzyme · Metabolism

NAD+ 1000mg

Central redox coenzyme · cellular energy and metabolism

Purity
≥99%
Format
1000mg
Route
Subcutaneous
Target
Sirtuins
For research use only (RUO) Ships from Quito · EC 1-3 days · LATAM 4-10 Arrives damaged? We replace it free COA per batch
CAS · 53-84-9 MW · 663.4 Da Stock · Available
Honest about the evidence

Human evidence for injectable NAD+ is limited. Almost all published clinical studies use oral NAD+/NMN (one systematic review pools 10 controlled trials, ~489 patients). The injectable raises blood NAD+ levels, but raising NAD+ ≠ proven clinical benefit. We position it as a continuous backbone of the mito-stack and longevity protocols, not as a weight-loss piece — there is even a signal that NAD+/NMN may blunt exercise's benefit on glucose. We say it plainly: this is a research compound, not a clinical promise.

How it works

4 axes. Central redox coenzyme.

NAD+ is the coenzyme that shuttles electrons in every cell. It is a cofactor for the sirtuins and PARPs. Its levels fall with age — hence the idea of replenishing it.

Energy / metabolism

The strongest signal. NAD+ is central to the chain that produces ATP. Research in cellular energy and fatigue.

Sirtuins

An obligate cofactor for the sirtuins, enzymes tied to cellular repair and regulation. The longevity rationale.

Cognition (modest)

Some signals in mental clarity and mood. Modest, non-conclusive evidence. Not its primary use.

Longevity (rationale)

Levels decline with age. Repletion is a reasonable hypothesis, not a proven clinical benefit in humans.

Recommended combinations

Combine with.

NAD+ works as a continuous backbone of the "mito-stack." It adds to mitochondrial peptides — not as a weight-loss booster.

NAD+ is a background backbone, not a weight booster. If you want weight loss, the piece is GLP-1, not NAD+.

The compound

Technical description.

NAD+ (nicotinamide adenine dinucleotide) is the central redox coenzyme of metabolism: a cofactor for the sirtuins and PARPs, and a key piece in cellular energy production. Its levels fall with age, which is where the idea of replenishing it directly by injection (subcutaneous) comes from — bypassing the low bioavailability of the oral route.

SuperBio Labs NAD+ is supplied as lyophilized powder with verified HPLC ≥99% purity. Each lot ships with an independent Certificate of Analysis confirming identity by LC-MS, content (98–102%), and endotoxin levels (<1.0 EU/mg).

Honest about the evidence level: human clinical evidence is weak for the injectable route — almost all of it comes from studies with oral NAD+/NMN. The injectable raises blood NAD+, but raising NAD+ does not equal a proven clinical benefit. Its best signal is energy and metabolism; cognition and longevity are positioning with thinner evidence. We use it as a continuous backbone of the mito-stack and longevity protocols, not as a weight-loss piece.

Product for informed professional use.

Complete kit · ready to reconstitute.

Each order includes everything needed for the cycle. No separate purchases required.

Vial + BWFI + syringes + alcohol swabs · kit contents
lyophilized NAD+ 1000mg vial
BWFI 10ml vial (bacteriostatic water)
30× insulin syringes U-100 0.5ml 29G
60× alcohol swabs (pre + post)
cycle organizer box
printed reconstitution guide
AM application protocol
batch COA (digital + printed)
Before you buy · from any store

How to choose where to buy peptides.

01
Per-batch, verifiable COA The certificate exists and can be checked — not "available on request".
02
HPLC purity + LC-MS identity How much is in the vial, and that it is the right compound.
03
Endotoxins tested LAL test within range — not just purity.
04
2-8°C cold chain Documented end to end, not promised.
05
Traceability and support Lot number on the vial and someone who answers after.

This product meets all five — your batch COA ships with the kit.

Recommended application protocol.

Conservative protocol included in the kit. Start low: early on, NAD+ can cause a flush (warmth, flushing) and stinging at the site. Inject slowly. Consult your physician before starting.

Reconstitution
10 ml bacteriostatic water → 100 mg/ml
Standard dose
50–100 mg/application
U-100 units (50mg)
50 units
Frequency
3–7 ×/week
Best timing
Morning · inject slowly (reduces the flush)
Loading phase
Weeks 1–2: low and more frequent dose, due to the flush
Maintenance
50–100 mg · 3–7×/week · continuous
Storage (reconstituted)
30 days refrigerated (2–8°C)

When to use NAD+.

Energy and metabolism

Its best signal · support for the cellular energy chain and fatigue.

Mito-stack backbone

Background cofactor alongside SS-31 / MOTS-c in mitochondrial protocols.

Longevity protocol

Rationale from the age-related drop in NAD+ · evidence still developing.

Cognition and mood

Modest signal in mental clarity · a secondary, not primary, use.

Quality of life in fatigue

Energy and sleep support in fatigue states · preliminary evidence.

Not for weight loss

Not a metabolic weight piece · may blunt exercise's effect on glucose.

Honest side effects.

Far more tolerable than the IV route, but not painless. Most reported:

Flush (warmth, flushing, sometimes nausea) mediated by the GPR109A receptor, especially if you inject fast or at a high dose · stinging at the subcutaneous injection site · both ease by starting low, ramping up slowly, and injecting slowly. There is no established universal protocol. If you take any metabolic or glucose treatment, consult your physician before combining.

Technical specifications

ProductNAD+
CAS Number53-84-9
Molecular Weight663.4 Da
Purity (HPLC)≥99%
FormatLyophilized powder
Quantity1000mg per vial
RouteSubcutaneous
Endotoxins<1.0 EU/mg
Storage−20 °C, protected from light
UseFor informed professional use
User guide

How is it applied, dosed, and stored?

Reconstitution, dosing, managing the flush, and safety flags for the NAD+ coenzyme.

Read the guide →

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