Tuftsin analog · calm without sedation · the Semax pairing
Selank is a heptapeptide analog of tuftsin, stabilized with a Pro-Gly-Pro tail. It calms anxiety without dulling you. That makes it different.
Allosteric action on the GABA system. Reduces anxiety without the sedation or dependence of benzodiazepines.
Increases the neurotrophic factor BDNF and modulates serotonin. The basis of its effect on mood and stress resilience.
Improves mental clarity without stimulation. That is why it pairs with Semax: baseline calm + focus on top.
Retains the immunomodulatory activity of the tuftsin it derives from. Studied in stress and general resilience.
Selank shines in cognitive stacks. With its calming profile (no stimulation), it complements the activating nootropics without overlapping.
If you take anxiolytics, antidepressants, or other psychiatric medication, consult your physician before combining.
Selank is a synthetic heptapeptide analog of tuftsin, with a stabilizing Pro-Gly-Pro tail added to resist degradation. It was developed in Russia, where it has been used as an anxiolytic since 2009. That combination of calm without sedation makes it a particularly interesting research tool in stress neuroscience and nootropics.
SuperBio Labs Selank is supplied as lyophilized powder with verified HPLC ≥99% purity. Each lot ships with an independent Certificate of Analysis confirming identity by LC-MS, peptide content (98–102%), and endotoxin levels (<1.0 EU/mg).
Its mechanism combines allosteric modulation of the GABA-A system, serotonin regulation, and an increase in BDNF (brain-derived neurotrophic factor), while retaining the immunomodulation of tuftsin. The result in the literature is reduced anxiety with no tolerance or dependence. In the research community Selank is best known as the Semax pairing: Semax provides activation and focus (AM) and Selank the calm (PM), together "calm + focus." Western evidence is limited — most studies are Russian or preclinical, with no Western Phase III clinical trials; we do not oversell it.
Informed professional research use only.
Each order includes everything needed for the cycle. No separate purchases required.
This product meets all five — your batch COA ships with the kit.
Conservative protocol included in the kit. If you take psychiatric medication (anxiolytics, antidepressants), consult your physician before starting.
Calm without sedation · no tolerance or dependence · its primary use.
Raises BDNF and modulates serotonin · resilience under stress.
Calm + focus · Semax AM, Selank PM · the classic cognitive stack.
Mental clarity without the overactivation of stimulants.
Retains the immunomodulation of tuftsin · sustained stress.
Only if sleep is broken by anxiety · weaker support.
Very benign. No serious effects documented in the available research literature:
Mild nasal irritation with the intranasal route · no tolerance or dependence described · long-term data in Western populations is limited (most evidence is Russian or preclinical). If you take psychiatric medication, consult your physician before combining.
| Product | Selank |
| CAS Number | 129954-34-3 |
| Molecular Weight | 751 Da |
| Purity (HPLC) | ≥99% |
| Format | Lyophilized powder |
| Quantity | 10mg per vial |
| Origin | Tuftsin analog (Pro-Gly-Pro) |
| Endotoxins | <1.0 EU/mg |
| Storage | −20 °C, protected from light |
| Use | Use under professional judgment |