5-Amino-1MQ

5-Amino-1MQ

Research peptide

Fat and muscle via the NNMT pathway

Early evidence
Research stage · preclinical · no human trialsWhat this means ›
🇺🇸 United States · Not approved

5-Amino-1MQ has no approval from any agency and no published clinical trials. Everything known comes from mice and cells.

Mouse results often do not carry over to people.

OverviewProtocolsPreparation and dosingEvidenceSafetyQuestions

Overview

What has it been researched for?

  • Reduces white fat without touching appetite Main focusEarly evidence
  • Stops NAD+ leaking from the cellEarly evidence
  • Preserves and protects muscleEarly evidence

Research protocols

The SBL research protocol and what the literature reports. Not medical advice.

SBL research protocol · no established clinical regimen in people

Dose
1 mg
Frequency
diario
Duration
6 weeks
Route
Subcutaneous
Evidence level
Preclinical

Tools

Reconstitution calculatorConverts mg to units (U-100), volume and concentration.Open calculator →Preparation (step by step)How to reconstitute, store and handle, with good practice.See the guide →My trackingLog doses, results and notes per goal, in the app.Go to my tracking →

Evidence and studies

See studies →
Strong evidence(0)Moderate evidence(0)Early evidence(3)

Protocols

Research protocols

SBL research protocol · no established clinical regimen in people

Research use, with no established clinical regimen in people.

Dose
1 mg
Frequency
diario
Timing
mañana
Duration
6 weeks
Break
2 weeks
Route
Subcutaneous
Evidence level
Preclinical

Example dose

015306
6 u= 1 mg

30-unit U-100 insulin syringe · Starting dose of its protocol, with 3 ml of water in the 50 mg vial.

What it pairs with

  • NAD+ 5-Amino stops the NAD+ leak (NNMT) and NAD+ refills it: they go together.

Preparation and dosing

Quick reference

Vial50 mg
Diluent3 ml
Concentration16.67 mg/ml
1 unit =0.167 mg

Preparation

Diluent
Bacteriostatic water

Open calculator →See the guide →

Evidence

Each effect with its evidence level and, where available, its source.

Strong evidence(0)Moderate evidence(0)Early evidence(3)
  • Reduces white fat without touching appetitePreclinicalSee study · 2018
  • Stops NAD+ leaking from the cellPreclinicalSee study · 2018
  • Preserves and protects musclePreclinicalSee study · 2019

The science

Mechanisms, studies and references

NNMT inhibitor

Safety

It makes sense if you want

  • Trim your waistline
  • Lose weight — most potent
  • More muscle, strength & composition

It does not make sense if

  • Active cancer or oncology treatment in the last 5 years
  • Pregnancy or breastfeeding

Talk to your doctor first if this applies (3)

  • Type 2 diabetes / prediabetes
  • Severe liver impairment
  • Severe kidney impairment

The certificate of analysis (CoA) certifies the identity and purity of the batch. It does not certify safety of use.

Verify your batch →

For research use only (RUO). This consult is educational and does not replace your doctor.

Questions

Frequently asked questions

What is it reconstituted with, and how much?

With bacteriostatic water: 3 ml into the 50 mg vial, giving 16.67 mg/ml.

What is the starting dose of the research protocol?

1 mg, diario. This is the SBL research protocol, with no established clinical regimen in people.

How long is the cycle, and how long does a vial last?

6 weeks ON / 2 weeks OFF. At the starting dose, the 50 mg vial lasts ~7.1 sem.

Which route is used in research?

Subcutaneous.

When does it make no sense?

It makes no sense with: Active cancer or oncology treatment in the last 5 years, Pregnancy or breastfeeding. Details in the Safety tab.

What is it combined with?

It goes well with NAD+. The reasons are in the Protocols tab.

How do I check my batch?

With the code on the vial, in the verifier. The CoA certifies the identity and purity of the batch, not safety of use.

Verify your batch →

See kit

For research use only (RUO). This consult is educational and does not replace your doctor.