NNMT inhibitor · small molecule · fat metabolism
It acts inside the fat cell, not on appetite.
The enzyme that rises most in the fat of people with obesity.
Less nicotinamide diverted: more substrate for NAD+ and sirtuins.
Less white fat and smaller fat cells in mice.
Activates muscle stem cells in old animals.
Peptides often synergize. These are the most studied combinations with this product, and what outcome they target.
Any combination must respect each peptide's protocol. If you have doubts about dosing or timing, message us before starting.
5-Amino-1MQ is a small molecule (not a peptide) that blocks the NNMT enzyme, which is highly active in white fat. Blocking it lets the cell keep more NAD+ and SAM, two key pieces of its energy metabolism.
SuperBio Labs 5-Amino-1MQ is supplied as lyophilized powder with HPLC purity ≥99%, with a Certificate of Analysis per lot.
In mice on an obesogenic diet it lowered weight and white fat without changing food intake (Neelakantan, 2018). In old mice it improved muscle regeneration and strength (2019). There are no human trials: this is the most preclinical item in our catalog and we present it that way.
Informed professional research use only.
We don't just hand you the vial. Every 5-Amino-1MQ purchase includes everything you need to apply it safely, with a clear protocol and our team available 24/7.
Lyophilized · HPLC purity ≥99% · Batch with COA
Sterile diluent · 0.9% benzyl alcohol
21G needle · For peptide reconstitution
30 units · daily · 30-day cap
1 per application + 1 to reconstitute
Free app · Week-by-week protocol, product sheet and usage guide
8 steps · From opening the kit to application
App · Tracking · Human team 24/7
About supplies: the quantity of syringes and wipes adjusts automatically based on the presentation you choose. For extended cycles (5-Amino-1MQ, GHK-Cu and similar) we cap supplies at 30 days — beyond that, 29G insulin syringes and 70% alcohol wipes are pharmacy items available without prescription in any city.
This product meets all five — your batch COA ships with the kit.
The official protocol included in the kit. If you have pre-existing medical conditions, consult a professional before starting.
No ramp-up: 1 mg from week 1 through 6.
Combine with TB-500 for accelerated recovery. Local application recommended.
Belly fat that does not move with diet · acts in the fat cell, not on hunger.
Adds a pathway other than appetite · see Metabolic Stack.
Muscle regeneration in old animals · with strength training.
Supports cellular NAD+ · pairs with MOTS-c.
Lose fat without losing muscle · preclinical signal on both fronts.
No safety data in people. It has not been studied in clinical trials; what circulates are user reports.
Most often reported: mild digestive discomfort · headache · some insomnia if used late. Because it affects cell methylation, avoid it in pregnancy and breastfeeding. If you have kidney or liver disease, ask first.
| Also known as | 5-amino-1-methylquinolinium |
| Class | Small molecule (not a peptide) |
| Molecular target | NNMT (nicotinamide N-methyltransferase) |
| Purity (HPLC) | ≥99% |
| Format | Lyophilized powder |
| Quantity | 50 mg per vial |
| Endotoxins | <1.0 EU/mg |
| Storage | −20 °C, protected from light |
| Use | Use under professional judgment |