NAD+
Research peptideCentral redox coenzyme · cellular energy and metabolism
Overview
What has it been researched for?
- Improves insulin sensitivity Main focusEarly evidence
- Improves lipids and blood pressureEarly evidence
- More energy and physical performanceEarly evidence
- Cellular energy: raises NAD+ and ATPModerate evidence
- Cellular longevity: sirtuins and repairEarly evidence
Research protocols
The SBL research protocol and what the literature reports. Not medical advice.
SBL research protocol · no established clinical regimen in people
- Dose
- 25 → 50 mg
- Frequency
- 3×/semana · AM
- Duration
- 8 weeks
- Route
- Subcutaneous
- Evidence level
- Human pilot
Tools
Evidence and studies
See studies →Protocols
Research protocols
SBL research protocol · no established clinical regimen in people
Research use, with no established clinical regimen in people.
- Dose
- 25 → 50 mg
- Frequency
- 3×/semana · AM
- Timing
- mañana
- Duration
- 8 weeks
- Break
- No break
- Route
- Subcutaneous
- Evidence level
- Human pilot
Example dose
100-unit U-100 insulin syringe · Starting dose of its protocol, with 5 ml of water in the 500 mg vial.
30-unit U-100 insulin syringe · Starting dose of its protocol, with 5 ml of water in the 1000 mg vial.
What it pairs with
- 5-Amino-1MQpairs well
- SS-31pairs well
Preparation and dosing
Quick reference
Preparation
- Diluent
- Bacteriostatic water
Evidence
Each effect with its evidence level and, where available, its source.
- Improves insulin sensitivityExtrapolatedSee study · 2021
- Improves lipids and blood pressureExtrapolatedSee study · 2018
- More energy and physical performanceExtrapolatedSee study · 2021
- Cellular energy: raises NAD+ and ATPHuman pilotSee study · 2019
- Cellular longevity: sirtuins and repairPreclinicalSee study · 2014
The science
Mechanisms, studies and references
Sirtuin cofactor
Safety
It makes sense if you want
- More energy & active metabolism
- Longevity & deep anti-aging
- Trim your waistline
It does not make sense if
- Active cancer or oncology treatment in the last 5 years
- Pregnancy or breastfeeding
Talk to your doctor first if this applies (2)
- Cardiovascular disease
- Hypertension
The certificate of analysis (CoA) certifies the identity and purity of the batch. It does not certify safety of use.
Verify your batch →For research use only (RUO). This consult is educational and does not replace your doctor.
Questions
Frequently asked questions
What is it reconstituted with, and how much?
With bacteriostatic water: 5 ml into the 500 mg vial, giving 100 mg/ml.
What is the starting dose of the research protocol?
25 → 50 mg, 3×/semana · AM. This is the SBL research protocol, with no established clinical regimen in people.
How long is the cycle, and how long does a vial last?
8 weeks. At the starting dose, the 500 mg vial lasts ~3.7 sem.
Which route is used in research?
Subcutaneous.
When does it make no sense?
It makes no sense with: Active cancer or oncology treatment in the last 5 years, Pregnancy or breastfeeding. Details in the Safety tab.
What is it combined with?
It goes well with 5-Amino-1MQ, SS-31. The reasons are in the Protocols tab.
How do I check my batch?
With the code on the vial, in the verifier. The CoA certifies the identity and purity of the batch, not safety of use.
For research use only (RUO). This consult is educational and does not replace your doctor.